Virucidal Effects of the Steam Distillate from Houttuynia cordata and its Components on HSV-1, Influenza Virus, and HIV. [131], human K562 leukemia cells are treated for 0.5, 2, 6, or 24 h with apigenin, fisetin, quercetin, or myricetin and the amount of topo2–DNA intermediates is determined using the TARDIS assay. Location. Based on the test systems used for investigations on type II topoisomerase inhibition by flavonoids, different potencies for quercetin are reported, namely, IC50 = 40 [141], 87 [116], or 100 μM [142]. Myricetin acts as covalent topo1 poison stabilizing the enzyme/DNA cleavage complex, whereas for planar flavonoids such as quercetin or baicalein, DNA intercalative activities are proposed. In China the herb is referred to as the ‘fishy smell herb’ owing to the foul fishy smell the leaves emit when pressed hard. Is combined medication with natural medicine a promising therapy for bacterial biofilm infection? Bensasson et al. is a member of Saururaceae, a family mainly distributed in Eastern Asia. ZAC Wagner Wunderschöne Chamäleonpflanze Eidechsenschwanz (Houttuynia cordata) Sie erhalten von uns eine kräftige Einzelpflanze im 9 cm Topf. Planta Med, 61(3): 237-241. doi: 10.1055/s-2006-958063. Houttuynia cordata itself contains almost no toxicity, but if it is not undertaken clinically, it will still result in excellent injury to your body. Foliage is aromatic when bruised. However, evidence about topoisomerase inhibitory properties of these glycosylated derivatives is limited so far. Considering a fact that the final development of SARS symptom is similar to that of PF, digging the role of HC or its vapor monomers in PF would be more attractive. against inflammation and oxidative stress: A review, Khanchuila Shingnaisui, ... Jatin Kalita, in, Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects. These findings are supported by Lopez-Lazaro et al. Many ancient texts from Chinese Traditional Medicine, Ayurveda and Siddha, and Japanese Traditional medicine have documented the efficacy of H. cordata against oxidative stress and inflammation. To elucidate whether there are more pharmacological effects of this plant, this study was therefore, carried out to determine the anti-hyperglycemic and anti-hyperlipidemic effects of 80% ethanol extract of H. cordata (HCE). The compounds in H. cordata contribute to the superior antiviral efficacy of the EA fraction which lacked cytotoxicity in vitro and acute toxicity in vivo. By comparing quercetin and fisetin, it appears that the 5-hydroxy group contributes to enzyme inhibitory properties, but the requirement of this moiety seems to be less prominent [83,131]. This review aims to provide up-to-date and comprehensive information on the efficacy of H. cordata extracts as well as its bioactive compounds both in vitro and in vivo, against oxidative stress and inflammation. In LPS-induced rat RPF, HC vapor extract treatment evidently up-regulated the ratio of lymphocytes and mononuclear phagocytes at the 7th day, reduced the expression of TGF-β1 and Smad2/3, the content of lung Hyp (16.5 mg/kg) and serum LDH, and increased the expression of IFN-γ and Smad7 (Du et al., 2012). PubMed:Houttuynia cordata attenuates lipid accumulation via activation of AMP … 2020 Jan 7;12(1):49. doi: 10.3390/pharmaceutics12010049. Psidium guava, Alternanthera philoxeroides, Andrographis paniculata, A. indica, Boesenbergia rotunda, C. papaya, Cladogynos orientalis, Cladosiphon okamuranus, Cryptonemia crenulata, Cymbopogon citratus, Euphorbia hirta, Flagellaria indica, Gymnogongrus griffithsiae, Gymnogongrus torulosus, Hippophae rhamnoides, Houttuynia cordata, Leucaena leucocephala, Lippia alba and Lippia citriodora, Meristiella gelidium, Mimosa scabrella, M. charantia, O. sanctum, Piper retrofractum, P. guajava, Quercus lusitanica, Rhizophora apiculata, Tephrosia crassifolia, Tephrosia madrensis and Tephrosia viridiflora, Uncaria tomentosa, and Zostera marina were found to be effective for DENV from different investigations. Epub 2019 Apr 17. Houttuynia cordata. The plant is well known among the people of diverse cultures across Japan, Korea, China and North-East India for its medicinal properties. Clipboard, Search History, and several other advanced features are temporarily unavailable. Hier finden Sie die Testsieger an Cordata, während der erste Platz unseren Favoriten ausmacht. Assessment of subchronic toxicity of fermented Houttuynia Cordata thunb. Jin S, Lee S, Jeon JH, Kim H, Choi MK, Song IS. Using rodent model system. 3-n-Nonylpyrazole 195 was a natural pyrazole derivative isolated by Japanese worker in 1954 from Houttuynia cordata, a plant of the piperacae family from tropical Asia Fig. Huh HW, Na YG, Bang KH, Kim SJ, Kim M, Kim KT, Kang JS, Kim YH, Baek JS, Lee HK, Cho CW. Action: To remove toxic heat, to promote the drainange of pus, and to relieve dysuria. Fig. In experiments with Leishmania donovani type I topoisomerase, a preincubation with baicalein, luteolin, and quercetin with respective concentrations of 3, 5, and 15 μM leads to a complete loss of enzyme activity [128].
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